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Emi Kurimoto Selected Research

TAK-071

11/2021Therapeutic potential of TAK-071, a muscarinic M1 receptor positive allosteric modulator with low cooperativity, for the treatment of cognitive deficits and negative symptoms associated with schizophrenia.
1/2019TAK-071, a novel M1 positive allosteric modulator with low cooperativity, improves cognitive function in rodents with few cholinergic side effects.
1/2019In Vivo Pharmacological Comparison of TAK-071, a Positive Allosteric Modulator of Muscarinic M1 Receptor, and Xanomeline, an Agonist of Muscarinic M1/M4 Receptor, in Rodents.

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Emi Kurimoto Research Topics

Disease

5Schizophrenia (Dementia Praecox)
11/2021 - 11/2017
4Cognitive Dysfunction
11/2021 - 01/2018
4Diarrhea
01/2020 - 01/2018
4Alzheimer Disease (Alzheimer's Disease)
01/2019 - 01/2018
3Dementia (Dementias)
01/2020 - 01/2019
1Memory Disorders (Memory Loss)
01/2020
1Parkinson Disease (Parkinson's Disease)
01/2020
1Neurobehavioral Manifestations
11/2017
1Catalepsy
11/2017
1Mental Disorders (Mental Disorder)
01/2017
1Acute Promyelocytic Leukemia
07/2009
1Neurodegenerative Diseases (Neurodegenerative Disease)
07/2009

Drug/Important Bio-Agent (IBA)

5Cholinergic Agents (Cholinergics)IBA
11/2021 - 01/2019
4Muscarinic M1 ReceptorIBA
11/2021 - 01/2018
3TAK-071IBA
11/2021 - 01/2019
3Antipsychotic Agents (Antipsychotics)IBA
11/2021 - 11/2017
3Scopolamine (Hyoscine)FDA Link
01/2020 - 01/2018
2Dihydrotachysterol (AT 10)IBA
01/2019 - 01/2018
2G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
11/2017 - 01/2017
1Poly I-CIBA
11/2021
1SynucleinsIBA
01/2020
1Donepezil (Aricept)FDA LinkGeneric
01/2020
1Acetylcholine (Acetylcholine Chloride)FDA Link
01/2020
1Muscarinic Receptors (Muscarinic Acetylcholine Receptor)IBA
01/2019
1xanomelineIBA
01/2019
1Carboxylic AcidsIBA
01/2018
1QuinolonesIBA
01/2018
1LipopolysaccharidesIBA
07/2009
1tamibaroteneIBA
07/2009

Therapy/Procedure

2Therapeutics
11/2021 - 07/2009
1Oral Administration
07/2009